A severe allergic reaction known as anaphylaxis can occur if a person has an allergy to any of the ingredients in Wellbutrin.
If any of the following symptoms occur, medical assistance should be sought immediately: a skin rash, itching, trouble breathing, chest pain, or swelling of the face, tongue, or throat. Alcohol : This should be avoided or at least severely limited when using Wellbutrin, as it has been linked to neuropsychotic side effects in a few cases. Pregnancy and breastfeeding : Mouse studies have not shown that Wellbutrin is likely to harm a pregnancy or the developing fetus.
However, since drugs do not alway affect humans and animals in the same way, this drug should only be used in pregnancy and breast feeding if it cannot be avoided. Bipolar disorder : A major depressive episode can develop into the first signs of bipolar disorder. A doctor should monitor the patient for signs of this. Wellbutrin is not approved for use in bipolar disorder. Driving and use of machinery : Dizziness, tiredness, blurred vision, and a false sense of wellbeing can occur when using this drug.
Because of this, using heavy machinery or driving should be considered with caution. Overdose : In rare cases, an overdose has led to seizures. Anyone who may have taken an overdose should go to the hospital. A recent study examined how air pollutants impact brain networks to mediate changes in cognitive function and enhance the risk of depression. A new study investigates whether or not regularly consuming mushrooms might reduce the risk of developing depression.
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Depression's physical symptoms can include fatigue, appetite changes, sleeping more or less than usual, and pain. Learn more here. What is bupropion, or Wellbutrin? Medically reviewed by Alan Carter, Pharm.
All patients being treated with antidepressants for any indication should watch for and notify their healthcare provider for worsening symptoms, suicidality and unusual changes in behavior, especially during the first few months of treatment.
Last Updated: January This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists.
This information is for educational and informational purposes only and is not medical advice. This information contains a summary of important points and is not an exhaustive review of information about the medication. Always seek the advice of a physician or other qualified medical professional with any questions you may have regarding medications or medical conditions.
Never delay seeking professional medical advice or disregard medical professional advice as a result of any information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein.
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Know the warning signs Learn the common signs of mental illness in adults and adolescents. Mental health conditions Learn more about common mental health conditions that affect millions. Caution is advised with breastfeeding since bupropion does pass into breast milk. People with depression may have low levels of norepinephrine and dopamine. By blocking your brain from reabsorbing norepinephrine and dopamine, aminoketone medications such as Wellbutrin bupropion can increase norepinephrine and dopamine levels and treat the symptoms of depression.
However, they believe that its effects on dopamine might be responsible for at least some of its effectiveness as a smoking cessation aid. Instead, it may work by mimicking some of the effects of the nicotine in cigarettes, which also causes your brain to release extra dopamine. Bupropion is available in several dosages. Certain brands of bupropion may contain a different dosage per tablet.
For depression, a typical starting dosage of bupropion is mg to mg per day, taken either as mg tablets taken twice per day or a single mg extended-release bupropion tablet taken in the morning.
The maximum dosage of bupropion for depression is mg to mg per day. After three to four days, you may need to adjust your dosage of bupropion. Follow the dosage instructions provided by your healthcare provider to make sure you take the right amount of bupropion.
For smoking cessation, a typical starting dosage is one mg extended-release tablet per day for the first three days, followed by a dosage of mg per day, taken as two tablets taken at least eight hours apart, from day four. Based on your symptoms, health history, response to the medication and several other factors, your healthcare provider may adjust your dosage of bupropion over time. Like all antidepressants, bupropion can cause certain side effects. Most of the side effects that can occur with bupropion are minor and temporary.
However, there are also several potentially severe side effects that you should be aware of before using this medication. Some of the common side effects of bupropion include:.
Many of these side effects may be mild and often disappear over the course of several days or weeks. In general, bupropion is less likely to cause sexual dysfunction than other commonly prescribed antidepressants, such as SSRIs and tricyclic antidepressants. Like other antidepressants, bupropion may cause serious side effects. These side effects occur in a small percentage of bupropion users.
Serious side effects of bupropion include:. Mental health issues, such as panic attacks, changes in mood, impulsive behavior and worsened depression or anxiety. Possible side effects include:. There is also a risk it can increase seizures in people who are susceptible to them or who have a history of eating disorders.
Wellbutrin may also be present in breastmilk. They can help determine whether the benefits of treating your condition outweigh the risks of staying on Wellbutrin. The FDA puts a black box warning on certain prescription drug labels to bring attention to any serious or life-threatening risks that you need to be aware of.
Wellbutrin, like other antidepressants, carries a black box warning for the possible increased risk of suicidal thoughts or behaviors in children, teens, and young adults. It's important to talk to your doctor to discuss the benefits versus the risks of this medication and to remain in close contact with them while taking Wellbutrin.
If you are having suicidal thoughts, contact the National Suicide Prevention Lifeline at for support and assistance from a trained counselor. If you or a loved one are in immediate danger, call For more mental health resources, see our National Helpline Database. Wellbutrin and Zyban are both brand names for the drug bupropion. Wellbutrin has been approved by the FDA as an antidepressant, and Zyban has been approved to help people stop smoking.
If you smoke cigarettes and are prescribed Wellbutrin, you might find that it also acts as a smoking cessation drug. It does not contain nicotine; however, some smokers report that it removes their interest or desire to smoke.
While Wellbutrin is not a first-line medication for ADHD, it can be helpful in treating ADHD symptoms, particularly if you have co-existing conditions like depression and anxiety. It might be prescribed combined with another ADHD medication or as a stand-alone option. They will be able to help you decide if it is a good option for you. Learn the best ways to manage stress and negativity in your life. Ng QX. J Child Adolesc Psychopharmacol. Factors associated with seizure development after bupropion overdose: A review of the toxicology investigators consortium.
Clin Toxicol Phila. Bupropion for adults with attention-deficit hyperactivity disorder: Meta-analysis of randomized, placebo-controlled trials. Psychiatry Clin Neurosci.
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